Preprint
(2026). In vivo elastography of the human retina using light-evoked intrinsic actuation. bioRxiv.
Journal Articles
(2026). Uncertainty principle-guided intra-volume motion correction in full-field swept-source OCT for phase-stable retinal imaging. Optics Express.
(2026). Optoretinography reveals rapid rod photoreceptor movement upon rhodopsin activation. Light: Science & Applications, 15, 58.
(2026). Phase-corrected complex averaging improves signal-to-noise ratio for in vivo retinal imaging using optical coherence tomography. APL Photonics, 11, 026108.
(2025). Electromechanical deformation of biological neurons: an intrinsic marker for label-free functional neuroimaging. Journal of Physics D: Applied Physics, 58, 053002.
(2025). Interferometric imaging of the reversible rhodopsin dynamics in the living rat eye. Nature Communications, 16, 10730.
(2025). On the physiological processes underlying optoretinography. Biomedical Optics Express, 11, 4332-4352.
(2025). Phase-restoring subpixel image registration: enhancing motion detection performance in Fourier-domain optical coherence tomography. Journal of Physics D: Applied Physics, 58, 145102.
(2025). Retinal thermal deformations measured with phase-sensitive optical coherence tomography in vivo. Light: Science & Applications, 14, 151.
(2024). Light-evoked deformations in rod photoreceptors, pigment epithelium and subretinal space revealed by prolonged and multilayered optoretinography. Nature Communications, 15, 5156.
(2022). Endoscopic optical coherence tomography angiography using inverse SNR-amplitude decorrelation features and electrothermal micro-electro-mechanical system raster scan. Quantitative Imaging in Medicine and Surgery, 12, 3078-3091.
(2021). Automatic 3D adaptive vessel segmentation based on linear relationship between intensity and complex-decorrelation in optical coherence tomography angiography. Quantitative Imaging in Medicine and Surgery, 11, 895-906.
(2021). High performance OCTA enabled by combining features of shape, intensity, and complex decorrelation. Optics Letters, 46, 368-371.
(2021). ID-OCTA: OCT angiography based on inverse SNR and decorrelation features. Journal of Innovative Optical Health Sciences, 14, 2130001.
(2021). Noninvasive OCT angiography-based blood attenuation measurements correlate with blood glucose level in the mouse retina. Biomedical Optics Express, 12, 4680-4688.
(2020). Improvement of decorrelation-based OCT angiography by an adaptive spatial-temporal kernel in monitoring stimulus-evoked hemodynamic responses. IEEE Transactions on Medical Imaging, 39, 4286 - 4296.
Conference Proceedings
(2026). High-throughput 3D localization with aberration estimation in interferometric scattering microscopy via an approximate interferometric point spread function model. Digital Holography and Three-Dimensional Imaging.
(2026). Reversible isomerization of rhodopsin imaged in-vivo with phase-sensitive OCT. SPIE BiOS, Ophthalmic Technologies XXXVI.
(2024). Optoretinography reveals comprehensive nanoscopic dynamics of the outer retina in rodents. SPIE BiOS, Ophthalmic Technologies XXXIV.
(2023). In-vivo optophysiology in rodent eyes using phase-sensitive optical coherence tomography. European Conferences on Biomedical Optics.
Conference Abstracts
(2026). Investigating optoretinography signal variation in sodium iodate-treated mice. ARVO Annual Meeting Abstract.
(2026). Laterally referenced optoretinography (ORG) reveals absolute light-evoked displacements in the human retina. ARVO Annual Meeting Abstract.
(2025). Optoretinography in rodents reveals rod photoreceptor movements associated with rhodopsin activation. ARVO Annual Meeting Abstract.
(2025). Reversible isomerization of rhodopsin imaged in a living eye with phase-sensitive OCT. ARVO Annual Meeting Abstract.
(2024). Investigating the onset of phototransduction in rodents via optoretinography. ARVO Annual Meeting Abstract.
(2024). Spatially-resolved phase signal extraction in OCT reveals distinct light-evoked responses of photoreceptors and retinal pigment epithelium. SPIE BiOS, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII.
(2024). Unsupervised extraction of light-evoked outer retina dynamics in rodents with spatial heterogeneity. SPIE BiOS, Ophthalmic Technologies XXXIV.
(2023). Phase-restoring subpixel image registration and automated signal extraction for optoretinography using phase-sensitive OCTs. SPIE BiOS, Ophthalmic Technologies XXXIII.
(2023). Subpixel motion correction for phase-sensitive optical coherence tomography. SPIE BiOS, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII.
(2022). Imaging photoreceptor response in rodent eyes using phase-sensitive optical coherence tomography. ARVO Annual Meeting Abstract.
(2022). Noninvasive OCTA-based blood glucometry. SPIE BiOS, Dynamics and Fluctuations in Biomedical Photonics XIX.
(2021). Improvement of decorrelation-based OCT angiography by an adaptive spatial-temporal kernel in monitoring stimulus-evoked hemodynamic responses. SPIE BiOS, Dynamics and Fluctuations in Biomedical Photonics XVIII.
Patents
(2026). Phase-restoring translational shifting of multidimensional images. Singapore Patent No. 11202405743Y, Issued; PCT Application No. PCT/SG2023/050286.
(2024). Machine learning-based optoretinography using phase-sensitive optical coherence tomography. PCT Application No. PCT/SG2024/050050.